Until 1970’s, Middle East was low of interest to Turkey. Since the mid-1970’s the importance of Middle East to Turkey has increased gradually along with Turkey’s increased importance to Middle Eastern nations. In this study, Turkey's economic relations with the Middle East countries was evaluated with a special emphasise on trade. The current political and ideological structures in the Middle East region largely determine the economic relations between Turkey and the Middle East nations. In this regard, The future of the economic relations between Turkey and the Middle East will be influenced by new ideological and poitical climate of the region after the Arab Spring.